Oral Presentation Clinical Oncology Society of Australia Annual Scientific Meeting 2018

The WHO (2017) Classification: What's Changed? (#112)

Chris Hemmings 1
  1. Department of Anatomic Pathology, Canterbury Health Laboratories, Christchurch , New Zealand

GastroEnteroPancreatic NeuroEndocrine Tumours (GEPNET) were previously classified in the WHO 2010 Classification of Tumours of the Digestive System.  However pancreatic NET are also covered by the Classification of Tumours of Endocrine Organs, published in 2017, and this volume encompasses some more recent recommendations on classifying and grading NET.  Significant changes include alterations to proliferation index cutpoints for grading, subdivision of grade 3 tumours, and altered nomenclature of combined neuroendocrine and epithelial neoplasms. These changes will be outlined, and their implications for clinical management considered.  Some issues around the pathology reporting of GEPNET will also be discussed, as clinicians should be aware of potential sources of confusion in interpretation of pathology reports.